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Patterns and mechanisms of structural variations in human cancer

Next-generation sequencing technology has enabled the comprehensive detection of genomic alterations in human somatic cells, including point mutations, chromosomal rearrangements, and structural variations (SVs). Using sophisticated bioinformatics algorithms, unbiased catalogs of SVs are emerging fr...

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Detalles Bibliográficos
Autores principales: Yi, Kijong, Ju, Young Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082854/
https://www.ncbi.nlm.nih.gov/pubmed/30089796
http://dx.doi.org/10.1038/s12276-018-0112-3