Cargando…

CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells

We investigated the functional role of CEACAM1 in a spontaneous metastasis xenograft model of human melanoma in scid mice using BRAF wildtype MeWo cells with and without RNAi mediated knockdown of CEACAM1. Tumors from the xenograft model were subjected to whole genome expression analysis and metasta...

Descripción completa

Detalles Bibliográficos
Autores principales: Wicklein, Daniel, Otto, Benjamin, Suling, Anna, Elies, Eva, Lüers, Georg, Lange, Tobias, Feldhaus, Susanne, Maar, Hanna, Schröder-Schwarz, Jennifer, Brunner, Georg, Wagener, Christoph, Schumacher, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082866/
https://www.ncbi.nlm.nih.gov/pubmed/30089785
http://dx.doi.org/10.1038/s41598-018-30338-4