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CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells
We investigated the functional role of CEACAM1 in a spontaneous metastasis xenograft model of human melanoma in scid mice using BRAF wildtype MeWo cells with and without RNAi mediated knockdown of CEACAM1. Tumors from the xenograft model were subjected to whole genome expression analysis and metasta...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082866/ https://www.ncbi.nlm.nih.gov/pubmed/30089785 http://dx.doi.org/10.1038/s41598-018-30338-4 |