Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3

Lysyl hydroxylases catalyze hydroxylation of collagen lysines, and sustain essential roles in extracellular matrix (ECM) maturation and remodeling. Malfunctions in these enzymes cause severe connective tissue disorders. Human lysyl hydroxylase 3 (LH3/PLOD3) bears multiple enzymatic activities, as it...

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Detalles Bibliográficos
Autores principales: Scietti, Luigi, Chiapparino, Antonella, De Giorgi, Francesca, Fumagalli, Marco, Khoriauli, Lela, Nergadze, Solomon, Basu, Shibom, Olieric, Vincent, Cucca, Lucia, Banushi, Blerida, Profumo, Antonella, Giulotto, Elena, Gissen, Paul, Forneris, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082870/
https://www.ncbi.nlm.nih.gov/pubmed/30089812
http://dx.doi.org/10.1038/s41467-018-05631-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082870/
https://www.ncbi.nlm.nih.gov/pubmed/30089812
http://dx.doi.org/10.1038/s41467-018-05631-5

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