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Reaching for the Stars in the Brain: Polymer-Mediated Gene Delivery to Human Astrocytes
Astrocytes, the “star-shaped” glial cells, are appealing gene-delivery targets to treat neurological diseases due to their diverse roles in brain homeostasis and disease. Cationic polymers have successfully delivered genes to mammalian cells and hence present a viable, non-immunogenic alternative to...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082920/ https://www.ncbi.nlm.nih.gov/pubmed/30081235 http://dx.doi.org/10.1016/j.omtn.2018.06.009 |