Cargando…
Reaching for the Stars in the Brain: Polymer-Mediated Gene Delivery to Human Astrocytes
Astrocytes, the “star-shaped” glial cells, are appealing gene-delivery targets to treat neurological diseases due to their diverse roles in brain homeostasis and disease. Cationic polymers have successfully delivered genes to mammalian cells and hence present a viable, non-immunogenic alternative to...
Autores principales: | Joshi, Chaitanya R., Raghavan, Vijay, Vijayaraghavalu, Sivakumar, Gao, Yue, Saraswathy, Manju, Labhasetwar, Vinod, Ghorpade, Anuja |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082920/ https://www.ncbi.nlm.nih.gov/pubmed/30081235 http://dx.doi.org/10.1016/j.omtn.2018.06.009 |
Ejemplares similares
-
Arginine-Modified Polymers Facilitate Poly (Lactide-Co-Glycolide)-Based Nanoparticle Gene Delivery to Primary Human Astrocytes
por: Proulx, Jessica, et al.
Publicado: (2020) -
Astrocyte HIV-1 Tat Differentially Modulates Behavior and Brain MMP/TIMP Balance During Short and Prolonged Induction in Transgenic Mice
por: Joshi, Chaitanya R., et al.
Publicado: (2020) -
Astrocyte elevated gene-1 regulates astrocyte responses to neural injury: implications for reactive astrogliosis and neurodegeneration
por: Vartak-Sharma, Neha, et al.
Publicado: (2012) -
HIV-1, methamphetamine and astrocytes at neuroinflammatory Crossroads
por: Borgmann, Kathleen, et al.
Publicado: (2015) -
Nanoparticle-mediated catalase delivery protects human neurons from oxidative stress
por: Singhal, A, et al.
Publicado: (2013)