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Differential Mechanisms of Septic Human Pulmonary Microvascular Endothelial Cell Barrier Dysfunction Depending on the Presence of Neutrophils

Sepsis is characterized by injury of pulmonary microvascular endothelial cells (PMVEC) leading to barrier dysfunction. Multiple mechanisms promote septic PMVEC barrier dysfunction, including interaction with circulating leukocytes and PMVEC apoptotic death. Our previous work demonstrated a strong co...

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Detalles Bibliográficos
Autores principales: Wang, Lefeng, Mehta, Sanjay, Ahmed, Yousuf, Wallace, Shelby, Pape, M. Cynthia, Gill, Sean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082932/
https://www.ncbi.nlm.nih.gov/pubmed/30116240
http://dx.doi.org/10.3389/fimmu.2018.01743