Cargando…

Rosuvastatin Reduces Neuroinflammation in the Hemorrhagic Transformation After rt-PA Treatment in a Mouse Model of Experimental Stroke

Hemorrhagic transformation (HT) is a serious complication that stimulates inflammation during reperfusion therapy after acute ischemic stroke. Rosuvastatin, a 3-hydroxymethyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, might improve the outcome of HT by inhibiting neuroinflammation. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Dan, Liu, Yanfang, Mai, Hongcheng, Zang, Jiankun, Shen, Lingling, Zhang, Yusheng, Xu, Anding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082938/
https://www.ncbi.nlm.nih.gov/pubmed/30116175
http://dx.doi.org/10.3389/fncel.2018.00225