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Rosuvastatin Reduces Neuroinflammation in the Hemorrhagic Transformation After rt-PA Treatment in a Mouse Model of Experimental Stroke

Hemorrhagic transformation (HT) is a serious complication that stimulates inflammation during reperfusion therapy after acute ischemic stroke. Rosuvastatin, a 3-hydroxymethyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, might improve the outcome of HT by inhibiting neuroinflammation. T...

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Detalles Bibliográficos
Autores principales:	Lu, Dan, Liu, Yanfang, Mai, Hongcheng, Zang, Jiankun, Shen, Lingling, Zhang, Yusheng, Xu, Anding
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082938/ https://www.ncbi.nlm.nih.gov/pubmed/30116175 http://dx.doi.org/10.3389/fncel.2018.00225

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