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Elucidating the Underlying Functional Mechanisms of Breast Cancer Susceptibility Through Post-GWAS Analyses

Genome-wide association studies (GWAS) have identified more than 170 single nucleotide polymorphisms (SNPs) associated with the susceptibility to breast cancer. Together, these SNPs explain 18% of the familial relative risk, which is estimated to be nearly half of the total familial breast cancer ri...

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Detalles Bibliográficos
Autores principales: Rivandi, Mahdi, Martens, John W. M., Hollestelle, Antoinette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082943/
https://www.ncbi.nlm.nih.gov/pubmed/30116257
http://dx.doi.org/10.3389/fgene.2018.00280