Intratracheal Administration of siRNA Dry Powder Targeting Vascular Endothelial Growth Factor Inhibits Lung Tumor Growth in Mice

Inhalation therapy using small-interfering RNA (siRNA) is a potentially effective therapeutic strategy for lung cancer because of its high gene-silencing effects and sequence specificity. Previous studies reported that intratracheal administration of siRNA using pressurized metered dose inhalers or...

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Detalles Bibliográficos
Autores principales: Miwata, Kei, Okamoto, Hirokazu, Nakashima, Taku, Ihara, Daisuke, Horimasu, Yasushi, Masuda, Takeshi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, Shibata, Ayumi, Ito, Takaaki, Okuda, Tomoyuki, Hattori, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083018/
https://www.ncbi.nlm.nih.gov/pubmed/30092405
http://dx.doi.org/10.1016/j.omtn.2018.07.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083018/
https://www.ncbi.nlm.nih.gov/pubmed/30092405
http://dx.doi.org/10.1016/j.omtn.2018.07.009

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