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Intratracheal Administration of siRNA Dry Powder Targeting Vascular Endothelial Growth Factor Inhibits Lung Tumor Growth in Mice

Inhalation therapy using small-interfering RNA (siRNA) is a potentially effective therapeutic strategy for lung cancer because of its high gene-silencing effects and sequence specificity. Previous studies reported that intratracheal administration of siRNA using pressurized metered dose inhalers or...

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Detalles Bibliográficos
Autores principales:	Miwata, Kei, Okamoto, Hirokazu, Nakashima, Taku, Ihara, Daisuke, Horimasu, Yasushi, Masuda, Takeshi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, Shibata, Ayumi, Ito, Takaaki, Okuda, Tomoyuki, Hattori, Noboru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083018/ https://www.ncbi.nlm.nih.gov/pubmed/30092405 http://dx.doi.org/10.1016/j.omtn.2018.07.009

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