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Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation

BACKGROUND & AIMS: Uncontrolled liver proliferation is a key characteristic of liver cancer; however, the mechanisms by which this occurs are not well understood. Elucidation of these mechanisms is necessary for the development of better therapy. The oncogene Gankyrin (Gank) is overexpressed in...

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Detalles Bibliográficos
Autores principales: D’Souza, Amber M., Jiang, Yanjun, Cast, Ashley, Valanejad, Leila, Wright, Mary, Lewis, Kyle, Kumbaji, Meenasri, Shah, Sheeniza, Smithrud, David, Karns, Rebekah, Shin, Soona, Timchenko, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083020/
https://www.ncbi.nlm.nih.gov/pubmed/30109252
http://dx.doi.org/10.1016/j.jcmgh.2018.05.007