Decreased Rhamnose Metabolic Flux Improved Production of Target Proteins and Cell Flocculation in Pichia pastoris

Previously, several genes, including LRA1–LRA4 and LRAR, involved in rhamnose utilization pathway, were discovered in Pichia pastoris GS115; among them, LRA3 and LRA4 were considered as key rate-determining step enzymes. A P. pastoris expression platform based on the strong rhamnose-inducible promot...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Chengliang, Xu, Xinxin, Zhang, Xue, Zhang, Yuwei, Zhang, Yuhong, Zhang, Zhifang, Zhang, Wei, Liu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083212/
https://www.ncbi.nlm.nih.gov/pubmed/30116233
http://dx.doi.org/10.3389/fmicb.2018.01771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083212/
https://www.ncbi.nlm.nih.gov/pubmed/30116233
http://dx.doi.org/10.3389/fmicb.2018.01771

Ejemplares similares