Variation in Interleukin 6 Receptor Gene Associates With Risk of Crohn’s Disease and Ulcerative Colitis

Interleukin 6 (IL6) is an inflammatory cytokine; signaling via its receptor (IL6R) is believed to contribute to development of inflammatory bowel diseases (IBD). The single nucleotide polymorphism rs2228145 in IL6R associates with increased levels of soluble IL6R (s-IL6R), as well as reduced IL6R si...

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Detalles Bibliográficos
Autores principales: Parisinos, Constantinos A., Serghiou, Stylianos, Katsoulis, Michail, George, Marc Jonathan, Patel, Riyaz S., Hemingway, Harry, Hingorani, Aroon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083435/
https://www.ncbi.nlm.nih.gov/pubmed/29775600
http://dx.doi.org/10.1053/j.gastro.2018.05.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083435/
https://www.ncbi.nlm.nih.gov/pubmed/29775600
http://dx.doi.org/10.1053/j.gastro.2018.05.022

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