Cargando…

Variation in Interleukin 6 Receptor Gene Associates With Risk of Crohn’s Disease and Ulcerative Colitis

Interleukin 6 (IL6) is an inflammatory cytokine; signaling via its receptor (IL6R) is believed to contribute to development of inflammatory bowel diseases (IBD). The single nucleotide polymorphism rs2228145 in IL6R associates with increased levels of soluble IL6R (s-IL6R), as well as reduced IL6R si...

Descripción completa

Detalles Bibliográficos
Autores principales:	Parisinos, Constantinos A., Serghiou, Stylianos, Katsoulis, Michail, George, Marc Jonathan, Patel, Riyaz S., Hemingway, Harry, Hingorani, Aroon D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	W.B. Saunders 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083435/ https://www.ncbi.nlm.nih.gov/pubmed/29775600 http://dx.doi.org/10.1053/j.gastro.2018.05.022

Ejemplares similares

Low-density lipoprotein cholesterol and atrial fibrillation; A Mendelian randomization study using UK-Biobank data
por: Katsoulis, Michail, et al.
Publicado: (2017)

Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis
por: Parisinos, Constantinos A., et al.
Publicado: (2020)

Corrigendum to: “Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis” [J Hepatol (2020) 241-251]
por: Parisinos, Constantinos A., et al.
Publicado: (2020)

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
por: Wilman, Henry R., et al.
Publicado: (2019)

Elevated plasma triglyceride concentration and risk of adverse clinical outcomes in 1.5 million people: a CALIBER linked electronic health record study
por: Patel, Riyaz S., et al.
Publicado: (2022)

Weight Change and the Onset of Cardiovascular Diseases: Emulating Trials Using Electronic Health Records
por: Katsoulis, Michail, et al.
Publicado: (2021)

Crohn's disease and ulcerative colitis Surgical management
por: Wilkinson, A J
Publicado: (1996)

Mucosal Barrier in Ulcerative Colitis and Crohn's Disease
por: Dorofeyev, A. E., et al.
Publicado: (2013)

The safety of vedolizumab for ulcerative colitis and Crohn's disease
por: Colombel, Jean-Frédéric, et al.
Publicado: (2017)

Ulcerative Colitis and Crohn's Disease: Similarities and Distinctions
por: Sawyerr, Af M, et al.
Publicado: (1994)

Review of pregnancy in Crohn’s disease and ulcerative colitis
por: Laube, Robyn, et al.
Publicado: (2021)

Genetic Variation in the Familial Mediterranean Fever Gene (MEFV) and Risk for Crohn's Disease and Ulcerative Colitis
por: Villani, Alexandra-Chloé, et al.
Publicado: (2009)

Assessment of Inter-Laboratory Variation in the Characterization and Analysis of the Mucosal Microbiota in Crohn’s Disease and Ulcerative Colitis
por: Szamosi, Jake C., et al.
Publicado: (2020)

Expressing the Differences between Crohn Disease and Ulcerative Colitis
por: Wijmenga, Cisca
Publicado: (2005)

Carbohydrate Intake in the Etiology of Crohn's Disease and Ulcerative Colitis
por: Chan, Simon S. M., et al.
Publicado: (2014)

The Changing Prognosis of Ulcerative Colitis and Crohn Disease by Decades
por: Korelitz, Burton I, et al.
Publicado: (2021)

Diagnosis of Crohn’s disease and ulcerative colitis using the microbiome
por: Kang, Da-Yeon, et al.
Publicado: (2023)

Plasma microRNA Profile Differentiates Crohn’s Colitis From Ulcerative Colitis
por: Netz, Uri, et al.
Publicado: (2018)

A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service
por: Kuan, Valerie, et al.
Publicado: (2019)

Differential Intestinal Mucosa Transcriptomic Biomarkers for Crohn's Disease and Ulcerative Colitis
por: Dobre, Maria, et al.
Publicado: (2018)

INTERACTIONS AMONG INTERLEUKIN-6, C-REACTIVE PROTEIN AND INTERLEUKIN-6 (-174) G/C POLYMORPHISM IN THE PATHOGENESIS OF CROHN’S DISEASE AND ULCERATIVE COLITIS
por: Takač, Boris, et al.
Publicado: (2020)

Reproducible disease phenotyping at scale: Example of coronary artery disease in UK Biobank
por: Patel, Riyaz S., et al.
Publicado: (2022)

Soluble interleukin-2 receptors in ulcerative colitis
por: Nielsen, O. H., et al.
Publicado: (1993)

Is there a role for vedolizumab in the treatment of ulcerative colitis and Crohn’s disease?
por: Gilroy, Leah, et al.
Publicado: (2014)

Gastritis Associated with Initially Pediatric Crohn's Disease and Ulcerative Colitis
por: Basturk, Ahmet, et al.
Publicado: (2018)

Crohn’s Disease and Ulcerative Colitis Show Unique Cytokine Profiles
por: Nemeth, Zoltan H, et al.
Publicado: (2017)

Tofacitinib, two-faced Janus in ulcerative colitis and Crohn’s disease?
por: Biemans, Vince BC, et al.
Publicado: (2020)

Development of the symptoms and impacts questionnaire for Crohn's disease and ulcerative colitis
por: Dulai, Parambir S., et al.
Publicado: (2020)

Salivary Stress/Immunological Markers in Crohn’s Disease and Ulcerative Colitis
por: Finamore, Alberto, et al.
Publicado: (2020)

A comparison of diverticulitis in Crohn's disease versus ulcerative colitis
por: Persaud, Alana, et al.
Publicado: (2019)

Gut Microbiota and Metabolic Specificity in Ulcerative Colitis and Crohn's Disease
por: Sankarasubramanian, Jagadesan, et al.
Publicado: (2020)

Prevalence of endodontic infection in patients with Crohn´s disease and ulcerative colitis
por: Poyato-Borrego, Manuel, et al.
Publicado: (2021)

Differentially Expressed miRNAs in Ulcerative Colitis and Crohn’s Disease
por: Yarani, Reza, et al.
Publicado: (2022)

Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry
por: Biemans, Vince B. C., et al.
Publicado: (2020)

Data-driven identification of ageing-related diseases from electronic health records
por: Kuan, Valerie, et al.
Publicado: (2021)

An informatics consult approach for generating clinical evidence for treatment decisions
por: Lai, Alvina G., et al.
Publicado: (2021)

Genetic Variants at Chromosome 9p21 and Risk of First Versus Subsequent Coronary Heart Disease Events: A Systematic Review and Meta-Analysis
por: Patel, Riyaz S., et al.
Publicado: (2014)

Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog
por: Hingorani, Aroon D, et al.
Publicado: (2023)

Differences in Immunophenotyping of Mucosal Lymphocytes Between Ulcerative Colitis and Crohn’s Disease
por: Lee, Heung Bum, et al.
Publicado: (1997)

MicroRNA signatures differentiate Crohn’s disease from ulcerative colitis
por: Schaefer, Jeremy S, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4ec56ftu8bbjp0gh92ctik9b65