Severe Early Onset Obesity due to a Novel Missense Mutation in Exon 3 of the Leptin Gene in an Infant from Northwest India

Monogenic obesity, caused by mutations in one of the genes involved in the control of hunger and satiety, is a rare cause of early onset obesity (EOO). The most common of the single gene alterations affect the leptin gene (LEP), resulting in congenital leptin deficiency that manifests as intense hyp...

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Detalles Bibliográficos
Autores principales: Dayal, Devi, Seetharaman, Keerthivasan, Panigrahi, Inusha, Muthuvel, Balasubramaniyan, Agarwal, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083471/
https://www.ncbi.nlm.nih.gov/pubmed/29217499
http://dx.doi.org/10.4274/jcrpe.5501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083471/
https://www.ncbi.nlm.nih.gov/pubmed/29217499
http://dx.doi.org/10.4274/jcrpe.5501

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