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The Effect of Citalopram on Genome-Wide DNA Methylation of Human Cells
Commonly used pharmaceutical drugs might alter the epigenetic state of cells, leading to varying degrees of long-term repercussions to human health. To test this hypothesis, we cultured HEK-293 cells in the presence of 50 μM citalopram, a common antidepressant, for 30 days and performed whole-genome...
Autores principales: | Kanherkar, Riya R., Getachew, Bruk, Ben-Sheetrit, Joseph, Varma, Sudhir, Heinbockel, Thomas, Tizabi, Yousef, Csoka, Antonei B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083487/ https://www.ncbi.nlm.nih.gov/pubmed/30148158 http://dx.doi.org/10.1155/2018/8929057 |
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