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The Effect of Citalopram on Genome-Wide DNA Methylation of Human Cells

Commonly used pharmaceutical drugs might alter the epigenetic state of cells, leading to varying degrees of long-term repercussions to human health. To test this hypothesis, we cultured HEK-293 cells in the presence of 50 μM citalopram, a common antidepressant, for 30 days and performed whole-genome...

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Detalles Bibliográficos
Autores principales: Kanherkar, Riya R., Getachew, Bruk, Ben-Sheetrit, Joseph, Varma, Sudhir, Heinbockel, Thomas, Tizabi, Yousef, Csoka, Antonei B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083487/
https://www.ncbi.nlm.nih.gov/pubmed/30148158
http://dx.doi.org/10.1155/2018/8929057