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F-CphI represents a new homing endonuclease family using the Endo VII catalytic motif

BACKGROUND: There are six known families of homing endonucleases, LAGLIDADG, GIY-YIG, HNH, His-Cys box, PD-(D/E)-XK, and EDxHD, which are characterized by their conserved residues. Previously, we discovered a novel homing endonuclease F-CphI encoded by ORF177 of cyanophage S-PM2. F-CphI does not res...

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Detalles Bibliográficos
Autores principales: Fang, Xiaoting, Jiang, YongLiang, Li, Kim, Zeng, Qinglu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083498/
https://www.ncbi.nlm.nih.gov/pubmed/30100927
http://dx.doi.org/10.1186/s13100-018-0132-5