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Possible Enzymatic Downregulation of the Natriuretic Peptide System in Patients with Reduced Systolic Function and Heart Failure: A Pilot Study

BACKGROUND: In patients with reduced systolic function, the natriuretic peptide system affects heart failure (HF) progression, but the expression of key activating (corin) and degrading enzymes (neprilysin) is not well understood. METHODS AND RESULTS: This pilot study (n=48) compared plasma levels o...

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Detalles Bibliográficos
Autores principales: Zaidi, Syed S., Ward, Ryan D., Ramanathan, Kodangudi, Yu, Xinhua, Gladysheva, Inna P., Reed, Guy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083548/
https://www.ncbi.nlm.nih.gov/pubmed/30148170
http://dx.doi.org/10.1155/2018/7279036