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Possible Enzymatic Downregulation of the Natriuretic Peptide System in Patients with Reduced Systolic Function and Heart Failure: A Pilot Study
BACKGROUND: In patients with reduced systolic function, the natriuretic peptide system affects heart failure (HF) progression, but the expression of key activating (corin) and degrading enzymes (neprilysin) is not well understood. METHODS AND RESULTS: This pilot study (n=48) compared plasma levels o...
Autores principales: | Zaidi, Syed S., Ward, Ryan D., Ramanathan, Kodangudi, Yu, Xinhua, Gladysheva, Inna P., Reed, Guy L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083548/ https://www.ncbi.nlm.nih.gov/pubmed/30148170 http://dx.doi.org/10.1155/2018/7279036 |
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