Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases

BACKGROUND: Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease for which the genetic contribution is incompletely understood. METHODS: We conducted a joint analysis of 5,523,934 imputed SNPs in two newly-genotyped progressive supranuclear palsy cohorts, primarily derived from t...

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Detalles Bibliográficos
Autores principales: Chen, Jason A., Chen, Zhongbo, Won, Hyejung, Huang, Alden Y., Lowe, Jennifer K., Wojta, Kevin, Yokoyama, Jennifer S., Bensimon, Gilbert, Leigh, P. Nigel, Payan, Christine, Shatunov, Aleksey, Jones, Ashley R., Lewis, Cathryn M., Deloukas, Panagiotis, Amouyel, Philippe, Tzourio, Christophe, Dartigues, Jean-Francois, Ludolph, Albert, Boxer, Adam L., Bronstein, Jeff M., Al-Chalabi, Ammar, Geschwind, Daniel H., Coppola, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083608/
https://www.ncbi.nlm.nih.gov/pubmed/30089514
http://dx.doi.org/10.1186/s13024-018-0270-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083608/
https://www.ncbi.nlm.nih.gov/pubmed/30089514
http://dx.doi.org/10.1186/s13024-018-0270-8

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