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P19 Cells as a Model for Studying the Circadian Clock in Stem Cells before and after Cell Differentiation
In mammals, circadian rhythmicity is sustained via a transcriptional/translational feedback loop referred to as the canonical molecular circadian clock. Circadian rhythm is absent in undifferentiated embryonic stem cells; it begins only after differentiation. We used pluripotent P19 embryonal carcin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ubiquity Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083773/ https://www.ncbi.nlm.nih.gov/pubmed/30210566 http://dx.doi.org/10.5334/jcr.157 |