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P19 Cells as a Model for Studying the Circadian Clock in Stem Cells before and after Cell Differentiation

In mammals, circadian rhythmicity is sustained via a transcriptional/translational feedback loop referred to as the canonical molecular circadian clock. Circadian rhythm is absent in undifferentiated embryonic stem cells; it begins only after differentiation. We used pluripotent P19 embryonal carcin...

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Détails bibliographiques
Auteurs principaux: Mashhour, Abdullah, Al Mansour, Zainab, Al Hallaj, Al Shaima, Ali, Rizwan, Trivilegio, Thadeo, Boudjelal, Mohamed
Format: Online Article Texte
Langue:English
Publié: Ubiquity Press 2018
Sujets:
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083773/
https://www.ncbi.nlm.nih.gov/pubmed/30210566
http://dx.doi.org/10.5334/jcr.157