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Simulation of Stimulation: Cytokine Dosage and Cell Cycle Crosstalk Driving Timing-Dependent T Cell Differentiation

Triggering an appropriate protective response against invading agents is crucial to the effectiveness of human innate and adaptive immunity. Pathogen recognition and elimination requires integration of a myriad of signals from many different immune cells. For example, T cell functioning is not quali...

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Detalles Bibliográficos
Autores principales: Barberis, Matteo, Helikar, Tomáš, Verbruggen, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083814/
https://www.ncbi.nlm.nih.gov/pubmed/30116196
http://dx.doi.org/10.3389/fphys.2018.00879