Azithromycin Resistance through Interspecific Acquisition of an Epistasis-Dependent Efflux Pump Component and Transcriptional Regulator in Neisseria gonorrhoeae

Mosaic interspecifically acquired alleles of the multiple transferable resistance (mtr) efflux pump operon correlate with increased resistance to azithromycin in Neisseria gonorrhoeae in epidemiological studies. However, whether and how these alleles cause resistance is unclear. Here, we use populat...

Descripción completa

Detalles Bibliográficos
Autores principales: Wadsworth, Crista B., Arnold, Brian J., Sater, Mohamad R. Abdul, Grad, Yonatan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083905/
https://www.ncbi.nlm.nih.gov/pubmed/30087172
http://dx.doi.org/10.1128/mBio.01419-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083905/
https://www.ncbi.nlm.nih.gov/pubmed/30087172
http://dx.doi.org/10.1128/mBio.01419-18

Ejemplares similares