Igf2/H19 Imprinting Control Region (ICR): An Insulator or a Position-Dependent Silencer?

The imprinting control region (ICR) located far upstream of the H19 gene, in conjunction with enhancers, modulates the transcription of Igf2 and H19 genes in an allele-specific manner. On paternal inheritance, the methylated ICR silences the H19 gene and indirectly facilitates transcription from the...

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Detalles Bibliográficos
Autores principales: Banerjee, Subhasis, Smallwood, Alan, Lamond, Scott, Campbell, Stuart, Nargund, Geeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084035/
https://www.ncbi.nlm.nih.gov/pubmed/12806090
http://dx.doi.org/10.1100/tsw.2001.50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084035/
https://www.ncbi.nlm.nih.gov/pubmed/12806090
http://dx.doi.org/10.1100/tsw.2001.50

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