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Igf2/H19 Imprinting Control Region (ICR): An Insulator or a Position-Dependent Silencer?
The imprinting control region (ICR) located far upstream of the H19 gene, in conjunction with enhancers, modulates the transcription of Igf2 and H19 genes in an allele-specific manner. On paternal inheritance, the methylated ICR silences the H19 gene and indirectly facilitates transcription from the...
Autores principales: | Banerjee, Subhasis, Smallwood, Alan, Lamond, Scott, Campbell, Stuart, Nargund, Geeta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084035/ https://www.ncbi.nlm.nih.gov/pubmed/12806090 http://dx.doi.org/10.1100/tsw.2001.50 |
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