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Clinical and biological implications of IDH1/2 in acute myeloid leukemia with DNMT3A(mut)
PURPOSE: The incidence of DNMT3A mutations in acute myeloid leukemia (AML) is quite high and often confers a poorer prognosis. Another common gene involved in AML is IDH1/2. However, the influence of IDH1/2 mutations on outcomes in DNMT3A-mutated patients remains unknown. This study aims to determin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084071/ https://www.ncbi.nlm.nih.gov/pubmed/30122995 http://dx.doi.org/10.2147/CMAR.S157632 |