Sinomenine inhibits the growth of melanoma by enhancement of autophagy via PI3K/AKT/mTOR inhibition

BACKGROUND: Melanoma is a common skin tumor in adults with high metastasis and mortality rates. Thus, finding a better effective approach to treat melanoma has become very urgent. Sinomenine (SIN), the major active compound of Sinomenium acutum, has shown antitumorigenic activities in certain cancer...

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Detalles Bibliográficos
Autores principales: Sun, Zheng, Zheng, Lingling, Liu, Xujun, Xing, Wenlong, Liu, Xinhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084074/
https://www.ncbi.nlm.nih.gov/pubmed/30122899
http://dx.doi.org/10.2147/DDDT.S155798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084074/
https://www.ncbi.nlm.nih.gov/pubmed/30122899
http://dx.doi.org/10.2147/DDDT.S155798

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