Praziquantel–lipid nanocapsules: an oral nanotherapeutic with potential Schistosoma mansoni tegumental targeting

PURPOSE: Lipid nanocapsules (LNCs) have shown potential to increase the bioavailability and efficacy of orally administered drugs. However, their intestinal translocation to distal target sites and their implication in pharmacokinetic (PK)–pharmacodynamic (PD) relationships are yet to be elucidated....

Descripción completa

Detalles Bibliográficos
Autores principales: Amara, Rokaya O, Ramadan, Alyaa A, El-Moslemany, Riham M, Eissa, Maha M, El-Azzouni, Mervat Z, El-Khordagui, Labiba K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084080/
https://www.ncbi.nlm.nih.gov/pubmed/30122922
http://dx.doi.org/10.2147/IJN.S167285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084080/
https://www.ncbi.nlm.nih.gov/pubmed/30122922
http://dx.doi.org/10.2147/IJN.S167285

Ejemplares similares