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Praziquantel–lipid nanocapsules: an oral nanotherapeutic with potential Schistosoma mansoni tegumental targeting
PURPOSE: Lipid nanocapsules (LNCs) have shown potential to increase the bioavailability and efficacy of orally administered drugs. However, their intestinal translocation to distal target sites and their implication in pharmacokinetic (PK)–pharmacodynamic (PD) relationships are yet to be elucidated....
Autores principales: | Amara, Rokaya O, Ramadan, Alyaa A, El-Moslemany, Riham M, Eissa, Maha M, El-Azzouni, Mervat Z, El-Khordagui, Labiba K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084080/ https://www.ncbi.nlm.nih.gov/pubmed/30122922 http://dx.doi.org/10.2147/IJN.S167285 |
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