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Dual redundant sequencing strategy: Full‐length gene characterisation of 1056 novel and confirmatory HLA alleles

The high‐throughput department of DKMS Life Science Lab encounters novel human leukocyte antigen (HLA) alleles on a daily basis. To characterise these alleles, we have developed a system to sequence the whole gene from 5′‐ to 3′‐UTR for the HLA loci A, B, C, DQB1 and DPB1 for submission to the Europ...

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Detalles Bibliográficos
Autores principales: Albrecht, V., Zweiniger, C., Surendranath, V., Lang, K., Schöfl, G., Dahl, A., Winkler, S., Lange, V., Böhme, I., Schmidt, A. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084308/
https://www.ncbi.nlm.nih.gov/pubmed/28547825
http://dx.doi.org/10.1111/tan.13057