Selection of 12‐Hour Sustained‐Release Acetaminophen (Paracetamol) Formulation Through Comparison of Pharmacokinetic Profiles of 4 Sustained‐Release Prototype Formulations and Standard Acetaminophen Formulation: An Open‐Label, Randomized, Proof‐of‐Principle Pharmacokinetic Study

Acetaminophen (APAP; paracetamol), a widely used analgesic and antipyretic, is available in modified‐release and immediate‐release (IR) formulations requiring 3‐ or 4‐times‐daily dosing. This phase 1 open‐label crossover study compared pharmacokinetic profiles of single 2000‐mg doses of 4 different...

Descripción completa

Detalles Bibliográficos
Autores principales: Yue, Yong, Liu, Dongzhou J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084339/
https://www.ncbi.nlm.nih.gov/pubmed/28816033
http://dx.doi.org/10.1002/cpdd.368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084339/
https://www.ncbi.nlm.nih.gov/pubmed/28816033
http://dx.doi.org/10.1002/cpdd.368

Ejemplares similares