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Evaluation of chemical chaperones based on the monitoring of Bip promoter activity and visualization of extracellular vesicles by real‐time bioluminescence imaging

It is known that endoplasmic reticulum (ER) stress in cells and extracellular vesicles (EVs) plays a significant role in cancer cells, therefore the evaluation of compounds that can regulate ER stress and EV secretion would be a suitable system for further screening and development of new drugs. In...

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Detalles Bibliográficos
Autores principales: Horibe, Tomohisa, Okushima, Nanako, Torisawa, Aya, Akiyoshi, Ryutaro, Hatta‐Ohashi, Yoko, Suzuki, Hirobumi, Kawakami, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084373/
https://www.ncbi.nlm.nih.gov/pubmed/28929569
http://dx.doi.org/10.1002/bio.3388