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Evaluation of chemical chaperones based on the monitoring of Bip promoter activity and visualization of extracellular vesicles by real‐time bioluminescence imaging
It is known that endoplasmic reticulum (ER) stress in cells and extracellular vesicles (EVs) plays a significant role in cancer cells, therefore the evaluation of compounds that can regulate ER stress and EV secretion would be a suitable system for further screening and development of new drugs. In...
Autores principales: | Horibe, Tomohisa, Okushima, Nanako, Torisawa, Aya, Akiyoshi, Ryutaro, Hatta‐Ohashi, Yoko, Suzuki, Hirobumi, Kawakami, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084373/ https://www.ncbi.nlm.nih.gov/pubmed/28929569 http://dx.doi.org/10.1002/bio.3388 |
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