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cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53

Autophagy is important in regulating the balance between cell death and survival, with the tumor suppressor p53 as one of the key components in this interplay. We have previously utilized an in vitro model of the most common form of childhood cancer, B cell precursor acute lymphoblastic leukemia (BC...

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Detalles Bibliográficos
Autores principales: Skah, Seham, Richartz, Nina, Duthil, Eva, Gilljam, Karin M., Bindesbøll, Christian, Naderi, Elin Hallan, Eriksen, Agnete B., Ruud, Ellen, Dirdal, Marta M., Simonsen, Anne, Blomhoff, Heidi Kiil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084393/
https://www.ncbi.nlm.nih.gov/pubmed/30100998
http://dx.doi.org/10.18632/oncotarget.25758