Cargando…
Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells
Enhancers are genetic elements that regulate spatiotemporal gene expression. Enhancer function requires transcription factor (TF) binding and correlates with histone modifications. However, the extent to which TF binding and histone modifications functionally define active enhancers remains unclear....
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084406/ https://www.ncbi.nlm.nih.gov/pubmed/30033119 http://dx.doi.org/10.1016/j.stem.2018.06.014 |