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Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells

Enhancers are genetic elements that regulate spatiotemporal gene expression. Enhancer function requires transcription factor (TF) binding and correlates with histone modifications. However, the extent to which TF binding and histone modifications functionally define active enhancers remains unclear....

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Detalles Bibliográficos
Autores principales:	Barakat, Tahsin Stefan, Halbritter, Florian, Zhang, Man, Rendeiro, André F., Perenthaler, Elena, Bock, Christoph, Chambers, Ian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084406/ https://www.ncbi.nlm.nih.gov/pubmed/30033119 http://dx.doi.org/10.1016/j.stem.2018.06.014

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