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Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma

Cancer-derived extracellular vesicles (EVs) are membrane-enclosed structures of highly variable size. EVs contain a myriad of substances (proteins, lipid, RNA, DNA) that provide a reservoir of circulating molecules, thus offering a good source of biomarkers. We demonstrate here that large EVs (L-EV)...

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Detalles Bibliográficos
Autores principales: Vagner, Tatyana, Spinelli, Cristiana, Minciacchi, Valentina R., Balaj, Leonora, Zandian, Mandana, Conley, Andrew, Zijlstra, Andries, Freeman, Michael R., Demichelis, Francesca, De, Subhajyoti, Posadas, Edwin M., Tanaka, Hisashi, Di Vizio, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084494/
https://www.ncbi.nlm.nih.gov/pubmed/30108686
http://dx.doi.org/10.1080/20013078.2018.1505403