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Understanding sequencing data as compositions: an outlook and review
MOTIVATION: Although seldom acknowledged explicitly, count data generated by sequencing platforms exist as compositions for which the abundance of each component (e.g. gene or transcript) is only coherently interpretable relative to other components within that sample. This property arises from the...
Autores principales: | Quinn, Thomas P, Erb, Ionas, Richardson, Mark F, Crowley, Tamsyn M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084572/ https://www.ncbi.nlm.nih.gov/pubmed/29608657 http://dx.doi.org/10.1093/bioinformatics/bty175 |
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