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Relative Abuse of Crush-Resistant Prescription Opioid Tablets via Alternative Oral Modes of Administration
OBJECTIVE: Some crush-resistant tablet formulations (CRTs) reduce prescription opioid abuse by nonoral routes of administration (ROAs), especially insufflation and injection, while oral abuse increases. Oral abuse involving product manipulation vs swallowing whole for CRTs and comparators was examin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084581/ https://www.ncbi.nlm.nih.gov/pubmed/29016905 http://dx.doi.org/10.1093/pm/pnx151 |