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Relative Abuse of Crush-Resistant Prescription Opioid Tablets via Alternative Oral Modes of Administration

OBJECTIVE: Some crush-resistant tablet formulations (CRTs) reduce prescription opioid abuse by nonoral routes of administration (ROAs), especially insufflation and injection, while oral abuse increases. Oral abuse involving product manipulation vs swallowing whole for CRTs and comparators was examin...

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Detalles Bibliográficos
Autores principales: Butler, Stephen F, Black, Ryan A, Fleming, Alison B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084581/
https://www.ncbi.nlm.nih.gov/pubmed/29016905
http://dx.doi.org/10.1093/pm/pnx151