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Interneurons secrete prosaposin, a neurotrophic factor, to attenuate kainic acid-induced neurotoxicity
Prosaposin (PS) is a secretory neurotrophic factor, as well as a regulator of lysosomal enzymes. We previously reported the up-regulation of PS and the possibility of its axonal transport by GABAergic interneurons after exocitotoxicity induced by kainic acid (KA), a glutamate analog. In the present...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084830/ https://www.ncbi.nlm.nih.gov/pubmed/30135939 http://dx.doi.org/10.1016/j.ibror.2017.07.001 |