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Presence of insoluble Tau following rotenone exposure ameliorates basic pathways associated with neurodegeneration

Protein aggregation is an important feature of neurodegenerative disorders. In Alzheimer's disease (AD) protein aggregates are composed of hyperphosphorylated Tau and amyloid beta peptide (Aβ). Despite the involvement and identification of the molecular composition of these aggregates, their ro...

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Detalles Bibliográficos
Autores principales: Chaves, Rodrigo S., Kazi, Amajad I., Silva, Carolliny M., Almeida, Michael F., Lima, Raquel S., Carrettiero, Daniel C., Demasi, Marilene, Ferrari, Merari F.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084878/
https://www.ncbi.nlm.nih.gov/pubmed/30135926
http://dx.doi.org/10.1016/j.ibror.2016.09.001