Cargando…

Distinct amino acid motifs carrying multiple positive charges regulate membrane targeting of dysferlin and MG53

Dysferlin (Dysf) and mitsugumin53 (MG53) are two key proteins involved in membrane repair of muscle cells which are efficiently recruited to the sarcolemma upon lesioning. Plasma membrane localization and recruitment of a Dysf fragment to membrane lesions in zebrafish myofibers relies on the presenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Lu, Middel, Volker, Reischl, Markus, Strähle, Uwe, Nienhaus, G. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084962/
https://www.ncbi.nlm.nih.gov/pubmed/30092031
http://dx.doi.org/10.1371/journal.pone.0202052