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Distinct amino acid motifs carrying multiple positive charges regulate membrane targeting of dysferlin and MG53
Dysferlin (Dysf) and mitsugumin53 (MG53) are two key proteins involved in membrane repair of muscle cells which are efficiently recruited to the sarcolemma upon lesioning. Plasma membrane localization and recruitment of a Dysf fragment to membrane lesions in zebrafish myofibers relies on the presenc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084962/ https://www.ncbi.nlm.nih.gov/pubmed/30092031 http://dx.doi.org/10.1371/journal.pone.0202052 |