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Calcimimetic R-568 vasodilatory effect on mesenteric vascular beds from normotensive (WKY) and spontaneously hypertensive (SHR) rats. Potential involvement of vascular smooth muscle cells (vSMCs)

The potential role of calcimimetics as vasculotropic agents has been suggested since the discovery that calcium sensing receptors (CaSRs) are expressed in cardiovascular tissues. However, whether this effect is CaSR-dependent or -independent is still unclear. In the present study the vascular activi...

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Detalles Bibliográficos
Autores principales: Di Pietro, Natalia, Potenza, Maria Assunta, Di Silvestre, Sara, Addabbo, Francesco, Di Pietrantonio, Nadia, Di Tomo, Pamela, Pipino, Caterina, Mandatori, Domitilla, Palmerini, Carola, Failli, Paola, Bonomini, Mario, Montagnani, Monica, Pandolfi, Assunta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084966/
https://www.ncbi.nlm.nih.gov/pubmed/30092054
http://dx.doi.org/10.1371/journal.pone.0202354