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Calcimimetic R-568 vasodilatory effect on mesenteric vascular beds from normotensive (WKY) and spontaneously hypertensive (SHR) rats. Potential involvement of vascular smooth muscle cells (vSMCs)
The potential role of calcimimetics as vasculotropic agents has been suggested since the discovery that calcium sensing receptors (CaSRs) are expressed in cardiovascular tissues. However, whether this effect is CaSR-dependent or -independent is still unclear. In the present study the vascular activi...
Autores principales: | Di Pietro, Natalia, Potenza, Maria Assunta, Di Silvestre, Sara, Addabbo, Francesco, Di Pietrantonio, Nadia, Di Tomo, Pamela, Pipino, Caterina, Mandatori, Domitilla, Palmerini, Carola, Failli, Paola, Bonomini, Mario, Montagnani, Monica, Pandolfi, Assunta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084966/ https://www.ncbi.nlm.nih.gov/pubmed/30092054 http://dx.doi.org/10.1371/journal.pone.0202354 |
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