DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF

DNA replication stress (DRS) leads to the accumulation of stalled DNA replication forks leaving a fraction of genomic loci incompletely replicated, a source of chromosomal rearrangements during their partition in mitosis. MUS81 is known to limit the occurrence of chromosomal instability by processin...

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Detalles Bibliográficos
Autores principales: Bétous, Rémy, Goullet de Rugy, Théo, Pelegrini, Alessandra Luiza, Queille, Sophie, de Villartay, Jean-Pierre, Hoffmann, Jean-Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085069/
https://www.ncbi.nlm.nih.gov/pubmed/30059501
http://dx.doi.org/10.1371/journal.pgen.1007541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085069/
https://www.ncbi.nlm.nih.gov/pubmed/30059501
http://dx.doi.org/10.1371/journal.pgen.1007541

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