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Functional aspects of meningeal lymphatics in aging and Alzheimer’s disease

Aging is a major risk factor for many neurological pathologies and the mechanisms underlying brain aging remain elusive. Unlike other tissues, the central nervous system (CNS) parenchyma is devoid of lymphatic vasculature and removal of waste products is performed mainly through a paravascular route...

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Detalles Bibliográficos
Autores principales: Da Mesquita, Sandro, Louveau, Antoine, Vaccari, Andrea, Smirnov, Igor, Cornelison, R. Chase, Kingsmore, Kathryn M., Contarino, Christian, Onengut-Gumuscu, Suna, Farber, Emily, Raper, Daniel, Viar, Kenneth E., Powell, Romie D., Baker, Wendy, Dabhi, Nisha, Bai, Robin, Cao, Rui, Hu, Song, Rich, Stephen S., Munson, Jennifer M., Lopes, M. Beatriz, Overall, Christopher C., Acton, Scott T., Kipnis, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085146/
https://www.ncbi.nlm.nih.gov/pubmed/30046111
http://dx.doi.org/10.1038/s41586-018-0368-8