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A single N(1)-methyladenosine on the large ribosomal subunit rRNA impacts locally its structure and the translation of key metabolic enzymes

The entire chemical modification repertoire of yeast ribosomal RNAs and the enzymes responsible for it have recently been identified. Nonetheless, in most cases the precise roles played by these chemical modifications in ribosome structure, function and regulation remain totally unclear. Previously,...

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Detalles Bibliográficos
Autores principales: Sharma, Sunny, Hartmann, Johannes David, Watzinger, Peter, Klepper, Arvid, Peifer, Christian, Kötter, Peter, Lafontaine, Denis L. J., Entian, Karl-Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085284/
https://www.ncbi.nlm.nih.gov/pubmed/30093689
http://dx.doi.org/10.1038/s41598-018-30383-z