NNMT depletion contributes to liver cancer cell survival by enhancing autophagy under nutrient starvation

Nicotinamide N-methyl transferase (NNMT) transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide (NAM), producing 1-methylnicotinamide (1MNA). NNMT has been implicated in several cancer types and recently in metabolism, but its role in autophagy regulation has not yet been invest...

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Detalles Bibliográficos
Autores principales: Shin, Ji Hye, Park, Chang Wook, Yoon, Gyesoon, Hong, Sun Mi, Choi, Kwan Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085294/
https://www.ncbi.nlm.nih.gov/pubmed/30093610
http://dx.doi.org/10.1038/s41389-018-0064-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085294/
https://www.ncbi.nlm.nih.gov/pubmed/30093610
http://dx.doi.org/10.1038/s41389-018-0064-4

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